The recent availability of schistosomal genome-sequence information allows protein identification in schistosome-derived samples by mass spectrometry (proteomics). Over the last few years, several proteome studies have been performed that addressed important questions in schistosome biology. This review summarizes the applied experimental approaches that have been used so far, it provides an overview of the most important conclusions that can be drawn from the performed studies and finally discusses future challenges in this research area.

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Keywords ESI, Host-parasite interaction, MALDI, MS, Proteome, SDS-PAGE, TOF, Tegument, electrospray ionisation, mass spectrometry, matrix assisted laser desorption ionization, sodium dodecyl sulfate-polyacrylamide gelelectrophoresis, time-of-flight
Persistent URL dx.doi.org/10.1016/j.exppara.2007.05.004, hdl.handle.net/1765/35138
Journal Experimental Parasitology
Citation
van Hellemond, J.J, van Balkom, B.W.M, & Tielens, A.G.M. (2007). Schistosome biology and proteomics: Progress and challenges. Experimental Parasitology (Vol. 117, pp. 267–274). doi:10.1016/j.exppara.2007.05.004