Sugammadex is the first selective relaxant binding agent and reverses rocuronium-induced neuromuscular block. A case is reported in which a patient accidentally received a high dose of sugammadex (40 mg kg-1) to reverse a rocuronium-induced (1.2 mg kg-1) profound neuromuscular block. A fast and efficient recovery from profound neuromuscular block was achieved and no adverse events or other safety concerns were reported.

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doi.org/10.1093/bja/aem057, hdl.handle.net/1765/35464
British Journal of Anaesthesia
Erasmus MC: University Medical Center Rotterdam

Molina, A.L, de Boer, H.D, Klimek, M, Heeringa, M, & Klein, J. (2007). Reversal of rocuronium-induced (1.2 mg kg-1) profound neuromuscular block by accidental high dose of sugammadex (40 mg kg-1). British Journal of Anaesthesia, 98(5), 624–627. doi:10.1093/bja/aem057