BACKGROUND: An increasing number of noninvasive, supraglottic airway devices are currently available. In this randomized single-blind study, we compared the Cobra Perilaryngeal Airway (CobraPLA) to the [Laryngeal Mask Airway (LMA)-Classic] during gynecological laparoscopy. METHODS: Forty patients received either an LMA-Classic or a CobraPLA. Insertion, ventilation and removal characteristics were noted, as well as any throat morbidity. RESULTS: Devices were similar for insertion characteristics, adverse events, and throat morbidity. Before pneumoperitoneum, peak airway pressures were 20.3 ± 4.9 cm H2O in the LMA-Classic group versus 25.5 ± 7.9 cm H2O in the CobraPLA group, P = 0.01. This difference was maintained during pneumoperitoneum; LMA-Classic (22.8 ± 6.1 cm H2O) and CobraPLA (28.1 ± 8.5 cm H2O), P = 0.04. Macroscopic blood occurred only on the CobraPLA, seen on 40% of the devices after removal, P = 0.001. CONCLUSION: During gynecological laparoscopy, the CobraPLA provides similar insertion characteristics, but higher airway sealing pressures than the LMA-Classic. The usefulness of this finding requires further investigation.,
Anesthesia and Analgesia
Erasmus MC: University Medical Center Rotterdam

Galvin, E., van Doorn, M., Blazquez, J., Ubben, J., Zijlstra, F., Klein, J., & Verbrugge, S. (2007). A randomized prospective study comparing the cobra perilaryngeal airway and laryngeal mask airway-classic during controlled ventilation for gynecological laparoscopy. Anesthesia and Analgesia, 104(1), 102–105. doi:10.1213/01.ane.0000246812.21391.d1