The objective of this study was to identify behavioral differences between children with multiple complex developmental disorder (MCDD) and those with pervasive developmental disorder-not otherwise specified (PDD-NOS). Twenty-five children (6-12 years) with MCDD and 86 children with PDD-NOS were compared with respect to psychiatric co-morbidity, psychotic thought problems and social contact problems using the child behavior checklist/4-18, the Dutch version of the diagnostic interview schedule for children-Version IV, the child and adolescent functional assessment scale, and the autism diagnostic observation schedule-generic. MCDD was associated with anxiety disorders, disruptive behavior, and psychotic thought problems. PDD-NOS was associated with deficits in social contact. MCDD differs from autistic disorder, and can also be delineated from PDD-NOS.

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Journal of Autism and Developmental Disorders
Erasmus MC: University Medical Center Rotterdam

de Bruin, E., de Nijs, P., Verheij, F., Hartman, C., & Ferdinand, R. (2007). Multiple complex developmental disorder delineated from PDD-NOS. Journal of Autism and Developmental Disorders, 37(6), 1181–1191. doi:10.1007/s10803-006-0261-4