Anti-Yo-associated paraneoplastic cerebellar degeneration is a cancer-related syndrome affecting the nervous system. This syndrome occurs almost exclusively in middle-aged women with gynecological cancers and it is rarerly found in patients with other types of cancer or in males. In this report we describe a male patient adenocarcinoma of the gastroesophageal junction and PCD with anti-Yo antibodies. To our knowledge, this is only the third report of PCD with positive anti-Yo antibodies in an esophageal tumor and the first report in a tumor of the gastroesophageal junction. Copyright

, , , ,,
Digestive Surgery
Erasmus MC: University Medical Center Rotterdam

Debes, J.D, Lagarde, S.M, Hulsenboom, E, Smitt, P.A, ten Kate, F.J.W, Sulter, G.A, & van Lanschot, J.J.B. (2007). Anti-Yo-associated paraneoplastic cerebellar degeneration in a man with adenocarcinoma of the gastroesophageal junction. Digestive Surgery, 24(5), 395–397. doi:10.1159/000107782