2007-03-01
In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin
Publication
Publication
Journal of Antimicrobial Chemotherapy , Volume 59 - Issue 3 p. 553- 555
Objectives: Eumycetoma caused by Madurella mycetomatis is treated with surgery and high doses of itraconazole and ketoconazole. These agents are toxic, and new therapies are required. Methods: MICs were determined for artemisinin and tea tree oil, two natural herbal compounds. Results: Artemisinin was not active against M. mycetomatis, but tea tree oil did inhibit its growth. Since tea tree oil's prime component easily penetrates the skin, tea tree oil could be a useful agent in the treatment of eumycetoma. Conclusions: Tea tree oil is active in vitro against M. mycetomatis.
Additional Metadata | |
---|---|
, , , , | |
doi.org/10.1093/jac/dkl526, hdl.handle.net/1765/36122 | |
Journal of Antimicrobial Chemotherapy | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
van de Sande, W., Fahal, A., Riley, T., Verbrugh, H., & van Belkum, A. (2007). In vitro susceptibility of Madurella mycetomatis, prime agent of Madura foot, to tea tree oil and artemisinin. Journal of Antimicrobial Chemotherapy, 59(3), 553–555. doi:10.1093/jac/dkl526 |