2007-06-01
Long-range DNA contacts: romance in the nucleus?
Publication
Publication
Current Opinion in Cell Biology , Volume 19 - Issue 3 p. 317- 320
Recent studies show that genes far apart on the same chromosome or even on different chromosomes can come together in the nuclear space. It has been hypothesized that functionally related genes 'kiss' at transcription factories to coordinate their expression. Novel high-throughput methods, such as 4C technology, that study DNA interactions in an unbiased manner should uncover the generality of this romantic concept of nuclear architecture.
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| doi.org/10.1016/j.ceb.2007.04.004, hdl.handle.net/1765/36455 | |
| Current Opinion in Cell Biology | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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de Laat, W. (2007). Long-range DNA contacts: romance in the nucleus?. Current Opinion in Cell Biology (Vol. 19, pp. 317–320). doi:10.1016/j.ceb.2007.04.004 |
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