PURPOSE OF REVIEW: To describe recent developments in the community-based approach of high-risk groups for Chlamydia trachomatis infection, and to discuss the assessment of impact of selective systematic screening on the transmission of C. trachomatis in the community. RECENT FINDINGS: Two large home-based screening programs in Europe have recently shown that systematic postal screening for C. trachomatis infection is feasible, but certain high-risk groups are poor participators. This underscores the need for risk selection and targeted approaches. A prediction rule has been developed which can assist in identifying high-risk groups and can be used as a tool for (self) selection for screening. The Internet has been shown to be a promising medium to promote chlamydia testing. School-based programs also succeed in including high-risk groups in screening programs. Recently developed dynamic simulation models, which take into account transmission of C. trachomatis, can assist in the development and evaluation of targeted screening strategies. SUMMARY: Chlamydia will not likely be controlled by one standard approach. Risk selection strategies need further development and different systematic approaches at the community level, including postal screening, school-based screening, and the Internet may produce the desired public health effect of decreasing morbidity and reducing the transmission of C. trachomatis in the community.

Chlamydia trachomatis, High-risk group, Prediction rule, Screening, Transmission modelling
dx.doi.org/10.1097/QCO.0b013e32801154fb, hdl.handle.net/1765/36523
Current Opinion in Infectious Diseases
Erasmus MC: University Medical Center Rotterdam

Richardus, J.H, & Götz, H.M. (2007). Risk selection and targeted interventions in community-based control of chlamydia. Current Opinion in Infectious Diseases (Vol. 20, pp. 60–65). doi:10.1097/QCO.0b013e32801154fb