About 4-10% of children and adolescents suffer from migraine. In the last few years, several studies have been performed to assess the efficacy and safety of triptans for the acute treatment of migraine in children and adolescents. Only sumatriptan nasal spray has been approved for the treatment of acute migraine with or without aura in adolescents aged 12-17 years in Europe. This review describes the results of the studies with sumatriptan nasal spray that have been performed in children and adolescents, including a study performed in the Netherlands.

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Keywords Adolescents, Children, Migraine, Placebo-controlled studies, Sumatriptan nasal spray
Persistent URL dx.doi.org/10.1016/j.ejpn.2007.02.010, hdl.handle.net/1765/36562
Journal European Journal of Paediatric Neurology
Callenbach, P.M.C, Pels, L.P.M, Mulder, P.G.H, Linssen, W.H.J.P, Gooskens, R.H.J.M, van der Zwan, J.L, & Brouwer, O.F. (2007). Sumatriptan nasal spray in the acute treatment of migraine in adolescents and children. European Journal of Paediatric Neurology (Vol. 11, pp. 325–330). doi:10.1016/j.ejpn.2007.02.010