This thesis particularly focused on the outcomes of constipation, celiac disease auto antibodies, asthma-like symptoms, and atopic dermatitis, which are all prevalent in the general population. In line with this, the main goals of this thesis were to assess: · Infant nutrition: o Consequences of timing of complementary feeding o Determinants of dietary patterns in toddlers · Gastrointestinal outcomes: o Consequences of celiac disease autoantibodies during pregnancy o Nutritional and endocrinological determinants of functional constipation in childhood · Asthma-like symptoms and atopic dermatitis: o Nutritional determinants of asthma-like symptoms and atopic dermatitis during the pre- and postnatal phase. These aims were explored within the framework of the Generation R Study, a population-based prospective multi-ethnic cohort study from fetal life onwards. The studies in this thesis particularly referred to the pre-school period of the child (i.e. from birth to 4 years of age).

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The studies described in this thesis were funded by the Erasmus Medical Center, the Erasmus University Rotterdam, the Netherlands Organization for Health Research and Development (Zon Mw) and Europe Container terminals (ECT). Financial support for printing of this thesis was kindly provided by: Erasmus University Rotterdam, Nederlandse Coeliakie Vereniging, J.E. Jurriaanse Stichting, Astmafonds, Danone Research – Center for Specialised Nutrition, Yakult Nederland B.V., Nutricia Nederland B.V., Nestlé Nutrition, GE Healthcare, Nutri-akt B.V. and Stichting Astmabestrijding Funders had no role in study design, data collection and analysis, decision to publish or preparation of the manuscript.
H.A. Moll (Henriëtte)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Kiefte-de Jong, J. (2012, September 12). Early life nutrition and gastrointestinal and allergic outcomes: the Generation R Study. Retrieved from