Breast cancer is the most frequent malignancy in women in Western Europe and the United States. In 2009, 13,177 new cases of breast cancer were diagnosed within the Netherlands alone The lifetime risk of breast cancer in Dutch women reached 1 in 8.3 between 2005 and 2009, which is comparable to the lifetime risk of 1 in 8.2 in United States women that was observed between 2005 and 2007. The European Standardized Rates of breast cancer in the Netherlands significantly increased from 97.4 per 100,000 in 1989 to 129.6 per 100,000 in 2007. This increase has been ascribed to lifestyle changes such as delayed childbearing, lower parity, reduced breast-feeding and increased body-mass index. At the same time, mortality rates have decreased slightly as a result of improved treatment and possibly as a result of population screening. Because of the increased incidence and slightly decreased mortality, the number of survivors has increased.

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M.M.B. Breteler (Monique)
Erasmus University Rotterdam
Financial support for the publication of this thesis was kindly provided by the Department of Epidemiology of the Erasmus University Medical Center, Rotterdam; the Erasmus University Rotterdam, Alzheimer Nederland, Lundbeck BV, Boehringer Ingelheim BV, and the Dutch Cancer Society.
Erasmus MC: University Medical Center Rotterdam

Koppelmans, V. (2012, April 20). Late effects of adjuvant chemotherapy on brain function and structure. Erasmus University Rotterdam. Retrieved from