1985-12-13
Eicosanoids, endotoxins and liver disease
Publication
Publication
Eicosanoiden, endotoxinen en leverziekten
Endotoxins are cell wall lipopolysacharides of gram negative bacteria. The gut contains large numbers of bacteria and is generally accepted to be a large reservoir of endotoxins. In the normal state absorbed endotoxins are rapidly removed from the portal blood by especially the reticulo-endothelial cells of the liver. In patients with liver disease there is a diminished function of the reticulo-endothelial system, resulting in a raised frequency of systemic endotoxemia. Systemic endotoxemia in liver disease, as measured by the Limulus lysate test, correlates with a higher frequency of clotting disorders, renal failure and a high mortality rate
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, , , | |
J.H.P. Wilson (Paul) , I.L. Bonta | |
Erasmus University Rotterdam | |
hdl.handle.net/1765/38751 | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Ouwendijk, R. (1985, December 13). Eicosanoids, endotoxins and liver disease. Retrieved from http://hdl.handle.net/1765/38751 |
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0454_OUWENDIJK, Robertus Jacobus Theodorus.jpg Cover Image , 96kb | |
Stellingen Ouwendijk.pdf , 26kb |