2012-11-01
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk
Publication
Publication
Nature Genetics , Volume 44 - Issue 11 p. 1- 3
We conducted a genome-wide association study of male breast cancer comprising 823 cases and 2,795 controls of European ancestry, with validation in independent sample sets totaling 438 cases and 474 controls. A SNP in RAD51B at 14q24.1 was significantly associated with male breast cancer risk (P = 3.02 × 10-13; odds ratio (OR) = 1.57). We also refine association at 16q12.1 to a SNP within TOX3 (P = 3.87 × 10-15; OR = 1.50).
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doi.org/10.1038/ng.2417, hdl.handle.net/1765/38813 | |
Nature Genetics | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Orr, N., Lemnrau, A., Cook, P., Fletcher, O., Tomczyk, K., Jones, M., … Swerdlow, A. (2012). Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk. Nature Genetics, 44(11), 1–3. doi:10.1038/ng.2417 |