The design of functional neuroimaging studies investigating the neural changes that support treatment-based recovery of targeted language functions in acquired aphasia faces a number of challenges. In this paper, we discuss these challenges and focus on experimental tasks and experimental designs that can be used to address the challenges, facilitate the interpretation of results and promote integration of findings across studies.

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Erasmus MC: University Medical Center Rotterdam

Rapp, B, Caplan, D, Edwards, S, Visch-Brink, E.G, & Thompson, C.K. (2013). Neuroimaging in aphasia treatment research: Issues of experimental design for relating cognitive to neural changes. NeuroImage (Vol. 73, pp. 200–207). doi:10.1016/j.neuroimage.2012.09.007