Due to immature antioxidant defenses, preterm infants are at susceptible to oxidative stress, which is associated with bronchopulmonary dysplasia, retinopathy of prematurity and periventricular leukomalacia. The general aim of this thesis was to study oxidative stress in preterm infants and to explore possible options to reduce the impact of oxidative stress in neonatal care. The studies presented in this thesis concern the optimal oxygen concentration for the resuscitation at birth, the effect of early parenteral nutriotion on oxidative stress and other modulators of oxidatove stress in preterm infants.

glutathione, oxidative stress, parenteral nutrition, preterm infants, resuscitation
J.B. van Goudoever (Hans)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Rook, D. (2013, April 17). Less Stress : Oxidative stress and glutathione kinetics in preterm infants. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/39675