Measles control remains a great challenge in Uganda. We conducted a prospective study among household contacts aged 9-59 months to assess measles vaccination effectiveness. Index cases were measles patients seen in Kampala hospitals in 1999. Measles was diagnosed in 37/43 (86%) of unvaccinated and in 33/145 (23%) of vaccinated exposed contacts, respectively. Vaccination effectiveness was 74% (95% CI; 64-81), which was lower than expected. This may indicate the need for strengthening of the cold chain and/or introduction of a second opportunity for measles vaccination, either as part of the routine immunization program or in the form of supplementary immunization activities.

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Journal Vaccine
Mupere, E, Karamagi, C, Zirembuzi, G, Grabowsky, M, de Swart, R.L, Nanyunja, M, & Mayanja, H. (2006). Measles vaccination effectiveness among children under 5 years of age in Kampala, Uganda. Vaccine, 24(19), 4111–4115. doi:10.1016/j.vaccine.2006.02.038