Due to improvements in pediatric cardio-thoracic surgery, anesthesia and diagnostics over the past decades, the number of adult patients with congenital heart disease (CHD) is growing. This causes an increasing demand in clinical practice for insight in long term outcome in both non-operated and operated adult CHD patients. Furthermore, knowledge about etiology and genetics of CHD is rapidly expanding. Every day new genes and syndromes are identified. In order to grasp the exact nature of the pathologies described in this thesis, the epidemiology of CHD and the functional anatomy of the left ventricular outflow tract and aorta will first be delineated. Thereafter, the congenital aortic disorders investigated in this thesis will be introduced individually. Finally, the aim and outline of this thesis will be presented.

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Biotronik Nederland B.V., Boehringer Ingelheim B.V., Cardialysis, Dutch Heart Foundation, Edwards Lifesciences, Erasmus University Rotterdam, GE Healthcare B.V., J.E. Jurriaanse Stichting, Merck Sharp & Dohme B.V., Roche Diagnostics Nederland B.V., Servier Nederland Farma B.V., St. Jude Medical Nederland B.V., Stichting Lijf en Leven
J.W. Roos-Hesselink (Jolien) , J.J.M. Takkenberg (Hanneke)
Erasmus University Rotterdam
hdl.handle.net/1765/39714
Erasmus MC: University Medical Center Rotterdam

van der Linde, D. (2013, April 19). Congenital Aortic Stenosis and Aneurysms. Retrieved from http://hdl.handle.net/1765/39714