Genome-wide association studies (GWAS) have substantially improved our understanding of the complex genetic architecture of many common traits. For the last decade, more than a thousand genetic variants were discovered using GWAS. The fast development of the field necessitated the improvement of existing instruments as well as the development of new ones. This thesis discusses methodology, software tools and new approaches facilitating the study of the complex genetic architecture of common traits.

Financial support by the Centre for Medical Systems Biology (CMSB) and Erasmus University for publication of this thesis is gratefully acknowledged.
C.M. van Duijn (Cornelia) , B.A. Oostra (Ben)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

Struchalin, M. (2013, May 22). Approaches to Dissect the Complex Genetic Architecture of Common Traits. Retrieved from