Tacrolimus: The balance between good and evil Pharmacogenetics in pediatric solid organ transplant recipients
Tacolimus: De balans tussen het goede en het kwade Pharmacogenetica en orgaantransplantatie in kinderen
Solid organ transplantation has dramatically increased the survival of both adult and children suffering from end-stage organ failure and improved the quality of life of these patients.With the introduction of calcineurin-inhibitors (CNIs) the short-term survival of transplant recipients improved even further. Presently, more than 90% of the immunosuppressive protocols in organ transplantation have CNIs incorporated as the primary immunosuppressant, resulting in CNIs being the mainstay of immunosuppressive therapy.
|Keywords||children, organ transplantation, pharmacokinetics|
|Promotor||D. Tibboel (Dick) , G. Koren (Gideon)|
|Publisher||Erasmus University Rotterdam|
Gijsen, V.M.G.J. (2013, May 30). Tacrolimus: The balance between good and evil Pharmacogenetics in pediatric solid organ transplant recipients. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/40544
|3758_Gijsen, Viola Margot Geertruida Johanna.jpg Cover Image , 72kb|