An overview is given on congenital heart disease in general and on tetralogy of Fallot (TOF) more specifically. Etiology and birth prevalences will be discussed, as well as treatment options and long-term outcome in TOF patients with regard to ventricular function and clinical condition. Since the right ventricle (RV) is the most affected ventricle in patients after TOF repair, more detailed information is given on RV anatomy, physiology, and function. Imaging techniques to assess systolic and diastolic function, in particular magnetic resonance imaging (MRI), will be discussed. The use of biomarkers in patients with heart failure and after TOF repair is described. Finally, the aims and outline of this thesis will be presented.

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The research described in this thesis was supported by a grant of the Dutch Heart foundation (DHF‐2006B095). Financial support by the Dutch Heart Foundation for the publication of this thesis is gratefully acknowledged. Additional financial support for the publication of this thesis was generously provided by Medis Medical Imaging systems, Erasmus University Rotterdam.
B.J.M. Mulder (Barbara) , W.A. Helbing (Willem)
Erasmus University Rotterdam
hdl.handle.net/1765/40677
Erasmus MC: University Medical Center Rotterdam

Luijnenburg, S. (2013, June 25). Outcome late after repair of teratology of Fallot. Retrieved from http://hdl.handle.net/1765/40677