Wrth the development of recombinant DNA technology a practically limitless amount of GH became available for clinical use. Against the background of the sizable literature, aims of the work in this thesis were to further investigate: a) optimal dose regimens regarding beneficial and harmful effects of the administration of pharmacological doses of GH in catabolic elderly adults. b) the possible role of GH as a stimulator of cancer growth or in the treatment of cancer induced cachexia in a tumor-bearing rat model. c) body compos~ion of GH deficient adults. d) the effects of chronic GH replacement in GH deficient adults.

Pharmacotherapy, adults, growth hormones, treatment
S.W.J. Lamberts (Steven)
Erasmus University Rotterdam
The support by Eli Lilly Nederland BV for the studies described in this thesis is gratefully acknowledged
Erasmus MC: University Medical Center Rotterdam

Binnerts, A. (1992, May 13). Growth hormone treatment in adults. Erasmus University Rotterdam. Retrieved from http://hdl.handle.net/1765/40709