We developed a computer program to analyze videodensity changes due to contrast appearance within a given operator-designated rectangle using two-dimensional echocardiograms previously recorded on videotape. Videodensity curves have been obtained from two-dimensional echocardiographic recordings in 14 patients after a total of 32 injections of 5% dextrose solution into the left ventricle during cardiac catheterization. The resulting videodensity vs time curves have some characteristics of indicator-dilution curves. The decay phase of these curves is largely mono-exponential. Potential clinical applications of this technique in measurement of ejection fraction, cardiac output and shunt quantification are discussed, as well as some potential limitations.

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Ultrasound in Medicine & Biology
Erasmus MC: University Medical Center Rotterdam

Meltzer, R., Bastiaans, O. L., Pierard, L., Serruys, P., Lancée, C. T., & Roelandt, J. (1982). Videodensitometric processing of contrast two-dimensional echocardiographic data. Ultrasound in Medicine & Biology, 8, 509–514. Retrieved from http://hdl.handle.net/1765/4076