Mechanical properties of mammalian single smooth muscle cells9

With the studies presented in this thesis it was attempted to achieve a discrimination between properties of smooth mus~ cle and of other components by measuring the passive and active properties of single smooth muscle cells isolated from both types of tissues. At the onset of the study experiments were solely performed on cells isolated from pig urinary bladders. which are quite similar to those of the human urinary bladder. In a later phase the study was extended to human uterine tissue fragments obtained at planned Caesarean sections. In order to achieve the goal of the study many practical and technical problems had to be solved. Some of the technical aspects have been published in international journals as a technical note or are embodied in the publications describing the results obtained. :Many others, although of crucial import: mce for the success of these experiments. especially in the field of cell and muscle physiology. were considered to have more practical and too little scientific value to be described in separate publications or in this thesis

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