Objective: Intensive image surveillance after endovascular aneurysm repair is generally recommended due to continued risk of complications. However, patients at lower risk may not benefit from this strategy. We evaluated the predictive value of the first postoperative computed tomography angiography (CTA) characteristics for aneurysm-related adverse events as a means of patient selection for risk-adapted surveillance. Methods: All patients treated with the Low-Permeability Excluder Endoprosthesis (W. L. Gore and Assoc, Flagstaff, Ariz) at a tertiary institution from 2004 to 2011 were included. First postoperative CTAs were analyzed for the presence of endoleaks, endograft kinking, distance from the lowermost renal artery to the start of the endograft, and for proximal and distal sealing length using center lumen line reconstructions. The primary end point was freedom from aneurysm-related adverse events. Multivariable Cox regression was used to test postoperative CTA characteristics as independent risk factors, which were subsequently used as selection criteria for low-risk and high-risk groups. Estimates for freedom from adverse events were obtained using Kaplan-Meier survival curves. Results: Included were 131 patients. The median follow-up was 4.1 years (interquartile range, 2.1-6.1). During this period, 30 patients (23%) sustained aneurysm-related adverse events. Seal length <10mmand presence of endoleak were significant risk factors for this end point. Patients were subsequently categorized as low-risk (proximal and distal seal length $10 mm and no endoleak, n[62) or high-risk (seal length<10mmor presence of endoleak, or both; n[69). During follow-up, four low-risk patients (3%) and 26 high-risk patients (19%) sustained events (P < .001). Four secondary interventions were required in three low-risk patients, and 31 secondary interventions in 23 high-risk patients. Sac growth was observed in two low-risk patients and in 15 high-risk patients. The 5-year estimates for freedom from aneurysm-related adverse events were 98% for the low-risk group and 52% for the high-risk group. For each diagnosis, 81.7 image examinations were necessary in the low-risk group and 8.2 in the high-risk group. Conclusions: Our results suggest that the first postoperative CTA provides important information for risk stratification after endovascular aneurysm repair when the Excluder endoprosthesis is used. In patients with adequate seal and no endoleaks, the risk of aneurysm-related adverse events was significantly reduced, resulting in a large number of unnecessary image examinations. Adjusting the imaging protocol beyond 30 days and up to 5 years, based on individual patients' risk, may result in a more efficient and rational postoperative surveillance. Copyright

abdominal aorta aneurysm, aged, angiography, article, computer assisted tomography, endoleak, endovascular surgery, female, follow up, human, male, methodology, postoperative care, predictive value, radiography, retrospective study, standard, time
dx.doi.org/10.1016/j.jvs.2012.11.085, hdl.handle.net/1765/40939
Journal of Vascular Surgery
Erasmus MC: University Medical Center Rotterdam

Gonçalves, F.B, van de Luijtgaarden, K.M, Hoeks, S.E, Hendriks, J.M, ten Raa, S.T, Rouwet, E.V, … Verhagen, H.J.M. (2013). Adequate seal and no endoleak on the first postoperative computed tomography angiography as criteria for no additional imaging up to 5 years after endovascular aneurysm repair. Journal of Vascular Surgery, 57(6), 1503–1511. doi:10.1016/j.jvs.2012.11.085