Predictive value of early maximal exercise test and thallium scintigraphy after successful percutaneous transluminal coronary angioplasty
British Heart Journal , Volume 53 p. 194- 200
Restenosis of the dilated vessel after percutaneous transluminal coronary angioplasty can be detected by non-invasive procedures but their ability to predict later restenosis soon after a successful angioplasty as well as recurrence of angina has not been assessed. A maximal exercise test and myocardial thallium perfusion scintigraphy were, therefore, performed in 91 asymptomatic patients a median of 5 weeks after they had undergone a technically successful angioplasty. Primary success of the procedure was confirmed by the decrease in percentage diameter stenosis from 64(12)% to 30(13)% as measured from the coronary angiograms and in the trans-stenotic pressure gradient (normalised for mean aortic pressure) from 0.61(0.16) to 0.17(0.09). A clinical follow up examination (8.6(4.9) months later) was carried out in all patients and a late coronary angiogram obtained in 77. The thallium perfusion scintigram showing the presence or absence of a reversible defect was highly predictive for restenosis whereas the exercise test was not. The positive predictive value of an abnormal scintigram was 82% compared with 60% for the exercise test (ST segment depression/or angina or both at peak workload). Angina or a new myocardial infarction occurred in 60% of patients with abnormal and in 21% of patients with normal scintigrams.
|*Angioplasty, Balloon, *Exercise Test, 0 (Radioisotopes), 7440-28-0 (Thallium), Adult, Aged, Angina Pectoris/diagnosis/*therapy, Female, Follow-Up Studies, Heart/*radionuclide imaging, Human, Male, Middle Aged, Radioisotopes/*diagnostic use, Recurrence, Thallium/*diagnostic use|
|British Heart Journal|
|Continued as: Heart|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Wijns, W, Serruys, P.W.J.C, Simoons, M.L, van den Brand, M.J.B.M, de Feyter, P.J, Reiber, J.H.C, & Hugenholtz, P.G. (1985). Predictive value of early maximal exercise test and thallium scintigraphy after successful percutaneous transluminal coronary angioplasty. British Heart Journal, 53, 194–200. Retrieved from http://hdl.handle.net/1765/4136