In the past decades the management of acute coronary syndromes (ACS), including myocardial infarction (MI) and unstable angina, has evolved from a strategy of watchful waiting to a highly technical intervention with anti-blood clotting drugs and percutaneous coronary intervention (PCI) with stent placement. As a result, the prognosis of patients has improved radically. In the 1960s in-hospital mortality in MI patients was as high as 30%. After the widespread introduction of coronary care units (CCU) in the 1970s this figure was reduced to approximately 15%, figure 1. Further improvements were made with the introduction of fibrinolytic drugs (1980s) and PCIs (1990s). Currently, 30 day mortality after MI admission has been reduced to 4 - 6 %.

Het verschijnen van dit proefschrift werd mede mogelijk gemaakt door de steun van de Nederlandse Hartstichting.
H. Boersma (Eric)
Erasmus University Rotterdam
Erasmus MC: University Medical Center Rotterdam

de Mulder, M. (2013, October 15). Glucose Regulation in Acute Coronary Syndromes: Implications for outcome and outcome prediction. Retrieved from