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B.E. Jaski, W. Wijns (William), R. Foulds and P.W.J.C. Serruys (Patrick)

1986

The haemodynamic and myocardial effects of dopexamine: a new B2-adrenoceptor and dopaminergic agonist

Publication

Publication

British Journal of Clinical Pharmacology , Volume 21 p. 393- 400

Dopexamine increases inotropic state and rate of relaxation independent of changes in heart rate. Dopexamine has a chronotropic effect and results in a decrease in systemic vascular resistance. Dopexamine has a spectrum of action that should be useful in patients with severe heart failure.

Additional Metadata
Keywords 0 (Adrenergic beta-Agonists), 0 (Receptors, Dopamine), 51-61-6 (Dopamine), 86197-47-9 (dopexamine), Adrenergic beta-Agonists/pharmacology, Adult, Aged, Blood Pressure/drug effects, Dopamine/*analogs & derivatives/pharmacology, Drug Evaluation, Female, Heart Failure, Congestive/drug therapy, Heart Rate/drug effects, Heart/*drug effects, Hemodynamic Processes/*drug effects, Human, Male, Middle Aged, Myocardial Contraction/drug effects, Receptors, Dopamine/drug effects, Support, U.S. Gov't, P.H.S., Vascular Resistance/drug effects
Persistent URL hdl.handle.net/1765/4183
Journal British Journal of Clinical Pharmacology
Note British Journal of Clinical Pharmacology
Organisation Erasmus MC: University Medical Center Rotterdam
Citation
Jaski, B. E., Wijns, W., Foulds, R., & Serruys, P. (1986). The haemodynamic and myocardial effects of dopexamine: a new B2-adrenoceptor and dopaminergic agonist. British Journal of Clinical Pharmacology, 21, 393–400. Retrieved from http://hdl.handle.net/1765/4183
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