Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study.
Catheterization and Cardiovascular Interventions , Volume 61 - Issue 4 p. 455- 460
The purpose of this study was to assess the safety and effectiveness of sirolimus-eluting stent (SES) postdilatation with largely oversized balloons. We evaluated the clinical outcome of 68 consecutive patients enrolled in the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry who underwent percutaneous coronary intervention with SES implantation and further postdilatation with balloons > 1 mm larger than the stent nominal size. Angiographic follow-up was either scheduled for selected subgroups or clinically driven. Overall, 75 lesions were treated. The procedure was successful in 98.5% of the cases. One patient (1.5%) underwent emergency coronary bypass surgery for acute vessel occlusion. During 10.1 +/- 1.7 months of follow-up, three patients (4.5%) died, one (1.5%) had acute myocardial infarction, and four (6%) had target vessel revascularization. At angiographic follow-up, loss index was 0.13 +/- 0.34 and restenosis rate was 7.7%. Although not routinely recommended in every patient, SES postdilatation with largely oversized balloons appears a safe and effective strategy for selected patients.
|*Balloon Dilatation, *Coronary Angiography, *Stents, Aged, Blood Vessel Prosthesis Implantation, Coated Materials, Biocompatible/*therapeutic use, Coronary Disease/diagnosis/therapy, Coronary Restenosis/etiology/radiography/surgery, Equipment Design, Female, Follow-Up Studies, Humans, Immunosuppressive Agents/*therapeutic use, Male, Middle Aged, Myocardial Infarction/diagnosis/therapy, Netherlands/epidemiology, Platelet Glycoprotein GPIIb-IIIa Complex/therapeutic use, Postoperative Complications/etiology/radiography/surgery, Reoperation, Sirolimus/*therapeutic use, Treatment Outcome, Ultrasonography, Interventional|
|Catheterization and Cardiovascular Interventions|
|Organisation||Erasmus MC: University Medical Center Rotterdam|
Saia, F, Lemos Neto, P.A, Arampatzis, C.A, Hoye, A, McFadden, E.P, Sianos, G, … de Feyter, P.J. (2004). Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study. Catheterization and Cardiovascular Interventions, 61(4), 455–460. doi:10.1002/ccd.20001