Currently, several different designs of coronary stents are available. However, only a few of the new generation stents have been investigated in large randomized trials. Mechanical behavior of first-generation stents (Palmaz-Schatz, Gianturco-Roubin) may not be applied to the new designs. We investigated the chronic mechanical behavior (recoil) of 2 stents recently approved by the Food and Drug Administration (MULTILINK and NIR). Forty-eight patients with single-stent implantation (23 MULTILINK and 25 NIR) were assessed by means of volumetric 3-dimensional intravascular ultrasound analysis after the procedure and at 6-month follow-up. In addition, volumetric assessment of neointimal formation was performed. No significant chronic stent recoil was detected in both groups (Δ MULTILINK stent volume: +5.6 ± 41 mm3 [p = NS] and Δ NIR stent volume + 2.1 ± 26 mm3 [p = NS]). A similar degree of neointimal formation at 6 months was observed between the 2 stents (MULTILINK 46 ± 31.9 mm3 vs NIR 39.9 ± 27.6 mm3, p = NS). In conclusion, these 2 second-generation tubular stents did not show chronic recoil and appeared to promote similar proliferative response after implantation in human coronary arteries.

coronary stents, stenosis,
The American Journal of Cardiology
Erasmus MC: University Medical Center Rotterdam

Costa, M.A, Sabaté, M, Kay, I.P, Kozuma, K, Serrano, P, de Valk, V, … de Feyter, P.J. (2000). Three-dimensional intravascular ultrasonic volumetric quantification of stent recoil and neointimal formation of two new generation tubular stents. The American Journal of Cardiology, 85(2), 135–139. doi:10.1016/S0002-9149(99)00655-4