Abstract

Influenza A virus is a member of the Orthomyxoviridae family. The influenza A viruses are classified on the basis of antigenic properties of the glycoproteins hemagglutinin (HA) and neuraminidase (NA) into 17 HA subtypes (H1-H17) and 10 NA subtypes (N1-N10) . These different subtypes of HA and NA are used in influenza A virus nomenclature, to discriminate viruses based on the surface glycoproteins (e.g. H5N1, H3N2). All subtypes with the exception of H17N10 circulate in wild birds, which are considered their natural reservoir. The H17N10 subtype has recently been isolated from bats, raising the possibility that birds are not the exclusive influenza virus reservoir. Influenza A virus is a single-stranded negative-sense segmented RNA virus, with a genome consisting of eight gene segments, that can encode up to 16 proteins (Fig 1a).

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E.J. Kuipers (Ernst) , I.D. de Beaufort (Inez) , E.W. Steyerberg (Ewout)
Financial support for this thesis was generously provided by: Erasmus University Rotterdam Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam, the Netherlands the Dutch Society of Gastroenterology J.E. Jurriaanse Stichting KWF Kankerbestrijding Dr. Falk Pharma Benelux B.V Vifor Pharma Nederland B.V. Olympus Nederland B.V. Zambon Nederland B.V. ERBE Nederland B.V. Pixels tregen Darmkanker en Vifor Pharma
Erasmus University Rotterdam
hdl.handle.net/1765/50165
Erasmus MC: University Medical Center Rotterdam

van Dam, L. (2013, September 25). Colorectal cancer screening: From test performance to participant experience. Retrieved from http://hdl.handle.net/1765/50165