2014-02-26
Polycystic ovary syndrome: from phenotype to genetype
Publication
Publication
Het polycysteus ovarium syndroom: van fenotype naar genotype
Abstract
oligomenorrhea or amenorrhea, hirsutism or hyperandrogenism and polycystic ovarian morphology. Later in life, adverse metabolic implications, such as obesity, insulin resistance, type 2 diabetes and cardiovascular disease, become more prominent. In this thesis, we aimed to identify genetic factors for PCOS susceptibility using a candidate-gene approach and a hypothesis-free genome-wide approach. Moreover, we have identified several high-risk groups for long-term health implications within the broad phenotype of PCOS.
| Additional Metadata | |
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| , , , | |
| J.S.E. Laven (Joop) , A.G. Uitterlinden (André) | |
| Erasmus University Rotterdam | |
| The printing of this thesis has been financially supported by the Department of Obstetrics and Gynaecology, Erasmus MC Rotterdam, the Erasmus University Rotterdam and Nederlandse Vereniging voor Obstetrie en Gynaecologie. Further support for this dissertation was kindly provided by: Goodlife Healthcare. | |
| hdl.handle.net/1765/50544 | |
| Organisation | Erasmus MC: University Medical Center Rotterdam |
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Louwers, Y. (2014, February 26). Polycystic ovary syndrome: from phenotype to genetype. Retrieved from http://hdl.handle.net/1765/50544 |
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