1991-04-24
Immunoregulatory and antitumor effects of interferon-γ
Publication
Publication
Immunoregulerende en antitumor effecten van interferon-γ
IFN-y was one of the first cytokines produced by recombinant DNA technology. After the production of recombinant DNA derived mouse and human IFN-y, recombinant DNA derived rat IFN-y became available. With this species-specific cytokine it has become possible to study biological effects of IFN-y in rats. Compared to the mouse model, the rat model is more suitable to study activities of IFN-y in tumor and organ transplantation experiments, since these experiments are technically far less demanding in rats. In this thesis multiple biological effects of rRIFN-y are studied in transplantation and tumor experiments in rats.
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Erasmus University Rotterdam | |
J. Jeekel (Hans) | |
hdl.handle.net/1765/50756 | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
IJzermans, J. (1991, April 24). Immunoregulatory and antitumor effects of interferon-γ. Retrieved from http://hdl.handle.net/1765/50756 |