Renal tract anomalies in the human fetus : prenatal ultrasound and genetic aspects.

In this thesis, attention will be focused on:(i) ultrasonic imaging of normal and abnormal fetal urinary tract anatomy;(ii) the reduced diagnostic potential of ultrasound in oligohydramnios, including methods to circumvent this problem; (iii) the association of ren al tract malforma ti ons and extrarenal and chromosomal anomalies which may have a decisive impact on obstetrie management. The objectives of the present study were: a. to define the role of ultrasound in the prenatal diagnosis of fetal urinary tract malforma ti ons, with particular reference to bilateral renal agenesis, cystic kidney disease and obstructive uropathy; b. to document the incidence and nature of associated extra-renal and chromosome anomalies; c. to assess perinatal outcome following prenatal diagnosis of a fetal urinary tract malformation; d. to establish the possibilities and Iimitations of prenatal ultrasound scanning in pregnancies at risk for a particular renal tract malformation; e. tb determine the potential of intra-uterine diversion techniques in obstructive uropathy.

• View at Worldcat

Free Full Text ( Final Version , 5mb )