Keypoints:
• An update of the literature on physical and psychosocial aspects of head and neck cancer, with special emphasis on effects of treatment, patient-related factors and psychosocial intervention on quality of life (QoL).
• QoL deteriorates during and directly after treatment and returns only slowly to pre-treatment values.
• Organ preservation, gender and coping-strategies are factors related to QoL after treatment.
• As prognosis and survival were found to be comparable under different treatment regimes, we noticed a gradual shift in therapy towards organ preservation.
• Systematic care, using specific instruments is important for improving the QoL.
• We feel that more attention should be given to improving support, in order to optimize the QoL of patients during the palliative stage.

doi.org/10.1111/j.1365-2273.2005.01035.x, hdl.handle.net/1765/52407
Clinical Otolaryngology
Department of Otorhinolaryngology

Ledeboer, Q., van der Velden, L. A., de Boer, M., Feenstra, L., & Pruyn, J. (2005). Physical and psychosocial correlates of head and neck cancer: An update of the literature and challenges for the future (1996-2003). Clinical Otolaryngology (Vol. 30, pp. 303–319). doi:10.1111/j.1365-2273.2005.01035.x