The feasibility of Tissue Harmonic Imaging with a prototype Intravascular Ultrasound (IVUS) system using a conventional single-element rotating IVUS catheter was investigated. Hydrophone measurements showed fundamental peak pressures of 1.9 MPa on-axis of such a catheter in water. The second harmonic signal at 40 MHz built up to 0.55 MPa, corresponding to 11 dB below the peak fundamental pressure. Experiments performed in a tissue-mimicking phantom and in a rabbit aorta in vivo showed the feasibility of Tissue Harmonic Imaging with a conventional IVUS catheter. When we applied averaging of four neighboring RF-lines in the in vivo acquisition, the Signal-to-Noise ratio of the harmonic image increased to 25 dB.

doi.org/10.1109/ULTSYM.2004.1417976, hdl.handle.net/1765/52557
2004 IEEE Ultrasonics Symposium
Department of Cardiology

Frijlink, M., Goertz, D., van Damme, L., Krams, R., & van der Steen, T. (2004). Intravascular Ultrasound Tissue Harmonic Imaging in vivo. Presented at the 2004 IEEE Ultrasonics Symposium. doi:10.1109/ULTSYM.2004.1417976