An improvement in myocardial longitudinal systolic velocities, assessed by pulsed-wave tissue Doppler imaging during low-dose dobutamine infusion, was observed at 6-month follow-up after 6 months of treatment with atorvastatin. Our findings indicate a favorable effect of atorvastatin on contractile reserve, possibly through an enhancement of flow-dependent coronary dilatation during stress.

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Journal The American Journal of Cardiology
Bountioukos, M, Rizzello, V, Krenning, E.P, Bax, J.J, Kertai, M.D, Vourvouri, E.C, … Poldermans, D. (2003). Effect of atorvastatin on myocardial contractile reserve assessed by tissue doppler imaging in moderately hypercholesterolemic patients without heart disease. The American Journal of Cardiology, 92(5), 613–616. doi:10.1016/S0002-9149(03)00737-9