2003-07-01
miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium
Publication
Publication
Annals of Human Genetics , Volume 67 - Issue 4 p. 372- 375
We describe software which calculates a set of linkage disequilibrium statistics, including multiallelic D′ corrected by the bootstrap and permutation. The software also provides a tool for maximum likelihood and least squares estimation and testing of a set of hierarchical hypotheses formulated within the framework of the Malecot model of the decay of linkage disequilibrium with distance. Additionally, the bootstrap approach is used for estimation of the model parameter's confidence intervals and for hypothesis testing. The programs are available from http://www.geneticepi.com/Research/software/software.html.
Additional Metadata | |
---|---|
doi.org/10.1046/j.1469-1809.2003.00041.x, hdl.handle.net/1765/57544 | |
Annals of Human Genetics | |
Organisation | Erasmus MC: University Medical Center Rotterdam |
Aulchenko, Y., Axenovich, T., Mackay, I., & van Duijn, C. (2003). miLD and booLD programs for calculation and analysis of corrected linkage disequilibrium. Annals of Human Genetics, 67(4), 372–375. doi:10.1046/j.1469-1809.2003.00041.x |