1990-02-01
Isolation of anonymous, polymorphic DNA fragments from human chromosome 22q12-qter
Publication
Publication
Human Genetics , Volume 84 - Issue 3 p. 219- 222
A series of 195 random chromosome 22-specific probes, equivalent to approximately 1% of the size of this chromosome, have been isolated from a chromosome 22-specific bacteriophage lambda genomic library. These probes were mapped to four different regions of chromosome 22 on a panel of five somatic cell hybrids. Restriction fragment length polymorphisms were detected by 28 of the probes mapping to 22q12-qter. Evolutionarily conserved sequences in human, mouse, and Chinese hamster DNA were detected by 12% of the isolated probes.
Additional Metadata | |
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doi.org/10.1007/BF00200562, hdl.handle.net/1765/59372 | |
Human Genetics | |
Organisation | Department of Medical Microbiology and Infectious Diseases |
Dumanski, J., Geurts van Kessel, A., Ruttledge, M., Wladis, A., Sugawa, N., Collins, P., & Nordenskjöld, M. (1990). Isolation of anonymous, polymorphic DNA fragments from human chromosome 22q12-qter. Human Genetics, 84(3), 219–222. doi:10.1007/BF00200562 |