2012-08-01
Genome stability, progressive kidney failure and aging
Publication
Publication
Nature Genetics , Volume 44 - Issue 8 p. 836- 838
Two new studies report mutations in FAN1 and three other genome-stability genes that tie the DNA damage response to progressive kidney failure and the dysfunction of several other organs. These findings provide clues to the underlying causes of tissue decline and may add a series of genes to the growing list of genome maintenance factors that protect against premature aging.
| Additional Metadata | |
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| doi.org/10.1038/ng.2363, hdl.handle.net/1765/59600 | |
| Nature Genetics | |
| Organisation | Department of Molecular Genetics |
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Lans, H., & Hoeijmakers, J. (2012). Genome stability, progressive kidney failure and aging. Nature Genetics, 44(8), 836–838. doi:10.1038/ng.2363 |
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