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G.S. Bleumink (Gysèle), I. Rietveld (Ingrid), J.A.M.J.L. Janssen (Joop), E.F.C. van Rossum (Liesbeth), A. Hofman (Albert), C.M. van Duijn (Cornelia), J.C.M. Witteman (Jacqueline), B.H.Ch. Stricker (Bruno) and J.W. Deckers (Jaap)

2004-08-01

Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study)

Publication

Publication

The American Journal of Cardiology , Volume 94 - Issue 3 p. 384- 386

We studied 4,963 participants of the population-based Rotterdam Study and found that a genetically determined chronic exposure to low insulin-like growth factor-I (IGF-I) levels is associated with an increased risk for heart failure in elderly patients.

Additional Metadata
Keywords *Genetic Predisposition to Disease, *Polymorphism (Genetics), 67763-96-6 (Insulin-Like Growth Factor I), Age Distribution, Alleles, Cardiovascular Disease, Cohort Studies, Comparative Study, Confidence Intervals, Female, Heart Failure, Congestive/*epidemiology/*genetics, Human, Incidence, Insulin-Like Growth Factor I/*genetics, Male, Prognosis, Promoter Regions (Genetics), Proportional Hazards Models, Prospective Studies, Risk Assessment, Sex Distribution, Survival Analysis
Persistent URL doi.org/10.1016/j.amjcard.2004.04.044, hdl.handle.net/1765/5978
Journal The American Journal of Cardiology
Organisation Erasmus MC: University Medical Center Rotterdam
Citation
Bleumink, G.S, Rietveld, I, Janssen, J.A.M.J.L, van Rossum, E.F.C, Hofman, A, van Duijn, C.M, … Deckers, J.W. (2004). Insulin-like growth factor-I gene polymorphism and risk of heart failure (the Rotterdam Study). The American Journal of Cardiology, 94(3), 384–386. doi:10.1016/j.amjcard.2004.04.044
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