1995-10-24
Structure and chromosomal localization of the human anti-mullerian hormone type II receptor gene
Publication
Publication
Biochemical and Biophysical Research Communications , Volume 215 - Issue 3 p. 1029- 1036
Using the rat anti-müllerian hormone type II receptor (AMHRII) cDNA as a probe, two overlapping lambda phage clones containing the AMHRII gene were isolated from a human genomic library. Sequence analysis of the exons was performed and the exon/intron boundaries were determined. The coding region was found to consist of 11 exons, divided over 8 kb. The genomic structure resembles that of the related activin type II receptor gene. The AMHRII gene was mapped to human chromosome 12q12-q13. The results reported are essential for identification of AMHRII gene alterations in patients with persistent müllerian duct syndrome.
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| doi.org/10.1006/bbrc.1995.2567, hdl.handle.net/1765/59900 | |
| Biochemical and Biophysical Research Communications | |
| Organisation | Department of Reproduction and Development |
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Visser, J., McLuskey, A., van Beers, T., Weghuis, D. O., Geurts van Kessel, A., Grootegoed, A., & Themmen, A. (1995). Structure and chromosomal localization of the human anti-mullerian hormone type II receptor gene. Biochemical and Biophysical Research Communications, 215(3), 1029–1036. doi:10.1006/bbrc.1995.2567 |
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