2004-10-18
Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors
Publication
Publication
British Journal of Cancer , Volume 91 - Issue 8 p. 1610- 1613
Local adenoviral gene transfer can be performed by means of isolated hepatic perfusion (IHP). This methodology is a very effective and safe way to deliver adenoviral vectors. We studied the immune response after IHP, A decreased neutralising antibody formation was observed, offering possibilities for further research in the field of gene therapy in isolated perfusion settings.
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| doi.org/10.1038/sj.bjc.6602151, hdl.handle.net/1765/60913 | |
| British Journal of Cancer | |
| Organisation | Department of Surgery |
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van Etten, B., Eggermont, A., Aan de Wiel-Ambagtsheer, G., van Tiel, S., & ten Hagen, T. (2004). Impaired neutralising antibody formation and high transduction efficacy after isolated hepatic perfusion with adenoviral vectors. British Journal of Cancer, 91(8), 1610–1613. doi:10.1038/sj.bjc.6602151 |
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