On MRI at 35 weeks of a boy born at 25 weeks, focal disorganization of the cortex was observed near a frontal venous infarct developed in the first week. Disruption of the final steps of cell migration, injury to the subplate and/or disruption of corticospinal axons are possible mechanisms behind it. Preterms with white matter lesions at or below 25 weeks postconceptional age should be scrutinized for cortical dysplasia.

Magnetic resonance imaging, Polymicrogyria, Postnatal, Venous infarction
dx.doi.org/10.1016/j.brainres.2006.08.093, hdl.handle.net/1765/61159
Brain Research
Department of Cardiology

Govaert, P, Lequin, M.H, Korsten, A, Swarte, R.M.C, Kroon, A.A, & Barkovich, J. (2006). Postnatal onset cortical dysplasia associated with infarction of white matter. Brain Research, 1121(1), 250–255. doi:10.1016/j.brainres.2006.08.093