Abstract
Blue rubber-bleb naevus (BRBN) syndrome is a rare disorder characterized by subcutaneous and gastrointestinal haemangiomas. The latter may lead to bleeding complications. A case is reported in which a process of chronic intravascular coagulation resulted in serious thrombotic complications. In the presence of a chronic consumption coagulopathy, it remains uncertain whether antiplatelet drugs are of prophylactic antithrombotic value.

aspirin, Blue rubber-bleb naevus, consumption coagulopathy, thrombosis
dx.doi.org/10.1007/BF01957684, hdl.handle.net/1765/61725
European Journal of Pediatrics
Department of Dermatology

Hofhuis, W, Oranje, A.P, Bouquet, J, & Sinaasappel, M. (1990). Blue rubber-bleb naevus syndrome: report of a case with consumption coagulopathy complicated by manifest thrombosis. European Journal of Pediatrics, 149(8), 526–528. doi:10.1007/BF01957684