The purpose of this case report is to report the orthodontic surgical treatment and subsequent dental rehabilitation in two patients with Axenfeld-Rieger syndrome. Axenfeld-Rieger syndrome is a rare autosomal dominant condition characterized by ocular, dental, craniofacial, and periumbilical abnormalities. The treatment of two patients with various anomalies in Axenfeld-Rieger syndrome is described and discussed. Early recognition of the syndrome and referral during childhood to a specialized oral and maxillofacial surgery, special dental care, and orthodontic unit provide the optimal starting point for this complex treatment.

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Cleft Palate - Craniofacial Journal
Department of Oral and Maxillofacial Surgery

Bender, C.A, Koudstaal, M.J, van Elswijk, J.F.A, Prahl, C, & Wolvius, E.B. (2014). Two cases of Axenfeld-Rieger syndrome, report of the complex pathology and treatment. Cleft Palate - Craniofacial Journal, 51(3), 354–360. doi:10.1597/12-295