Infant orthopedics in UCLP: Effect on feeding, weight, and length: A randomized clinical trial (Dutchcleft)
Cleft Palate - Craniofacial Journal , Volume 42 - Issue 2 p. 171- 177
Objective: To study the effects of infant orthopedics (IO) on feeding, weight, and length. Design: Prospective two-arm randomized controlled trial in three academic Cleft Palate Centers. Treatment allocation was concealed and performed by means of a computerized balanced allocation method. Setting: Cleft Palate Centers of Amsterdam, Nijmegen, and Rotterdam, the Netherlands. Patients: Infants with complete unilateral cleft lip and palate (UCLP), no other malformations. Interventions: One group (IO +) wore passive maxillary plates during the first year of life, but the other group (IO -) did not. All other interventions were the same for both groups. Main Outcome Measures: Bottle feeding velocity (mL/min) at intake, 3, 6, 15, and 24 weeks (T 0 to T 24); weight-for-age, length-for-age, and weight-for-length using z scores; reference values from the Netherlands' third nationwide survey on growth. Results: Feeding velocity increased with time from 2.9 to 13.2 mL/min in the IO - group and from 2.6 to 13.8 mL/min in the IO + group; no significant differences were found between groups. Weight-for-age, length-for-age, and weight-for-length (z scores) did not differ significantly between groups, but overall the infants with unilateral cleft lip and palate in both groups had significantly lower mean z scores for weight-for-age and height-for-age than the reference during the first 14 months, and had lower mean values for weight-for-length after soft palate closure. Conclusion: Infant orthopedics with the aim of improving feeding and consequent nutritional status in infants with unilateral cleft lip and palate can be abandoned.
|Cleft palate, Feeding, Infant orthopedics, Length, Maxilla, Multicenter, Randomized clinical trial, Weight|
|Cleft Palate - Craniofacial Journal|
|Organisation||Department of Plastic and Reconstructive Surgery|
Prahl, C, Kuijpers-Jagtman, A.M, Van't Hof, M.A, & Prahl-Andersen, B. (2005). Infant orthopedics in UCLP: Effect on feeding, weight, and length: A randomized clinical trial (Dutchcleft). Cleft Palate - Craniofacial Journal, 42(2), 171–177. doi:10.1597/03-111.1