Paravalvular leak after transcatheter aortic valve replacement: The new achilles' heel? A comprehensive review of the literature
Journal of the American College of Cardiology , Volume 61 - Issue 11 p. 1125- 1136
Paravalvular leak (PVL) is a frequent complication of transcatheter aortic valve replacement (TAVR) and is seen at a much higher rate after TAVR than after conventional surgical aortic valve replacement. Recent reports indicating that PVL may be correlated with increased late mortality have raised concerns. However, the heterogeneity of Methods: for assessing and quantifying PVL, and lack of consistency in the timing of such assessments, is a hindrance to understanding its true prevalence, severity, and effect. This literature review is an effort to consolidate current knowledge in this area to better understand the prevalence, progression, and impact of post-TAVR PVL and to help direct future efforts regarding the assessment, prevention, and treatment of this troublesome complication.
|Aortic stenosis, Paravalvular leak, TAVI, TAVR|
|Journal of the American College of Cardiology|
|Organisation||Department of Cardio-Thoracic Surgery|
Généreux, P, Head, S.J, Hahn, R.T, Daneault, B, Kodali, S, Williams, M.R, … Leon, M.B. (2013). Paravalvular leak after transcatheter aortic valve replacement: The new achilles' heel? A comprehensive review of the literature. Journal of the American College of Cardiology (Vol. 61, pp. 1125–1136). doi:10.1016/j.jacc.2012.08.1039