Objective: To assess whether liver transplant recipients have a hypoactive (sedentary) lifestyle and whether the level of everyday physical activity is related to complaints of fatigue. In addition, we explored the relationship between activity level and health-related quality of life. Design: Case comparison. Subjects. Eight persons 6-36 months after liver transplantation with varying severity of fatigue and 8 persons without known impairments (matched for gender, age, social situation and employment). Methods: Activity levels were assessed during 2 randomly selected consecutive weekdays with an accelerometry-based Activity Monitor. In the transplantation group, severity of fatigue (Fatigue Severity Scale) and health-related quality of life (RAND-36) were also assessed. Results: Five liver transplant recipients had a hypoactive lifestyle, but there was no significant difference in activity level between the transplantation group and comparison group. Severity of fatigue was correlated (p = 0.01) with both duration of dynamic activities and intensity of everyday activity (rs= -0.81 and -0.84, respectively). Activity level was correlated (p ≤ 0.05) with several domains of health-related quality of life (rs = 0.72-0.78). Conclusion: As a group, liver transplant recipients were not significantly less active than comparison subjects. Activity level was related with severity of fatigue and health-related quality of life. These findings have implications for the development of interventions needed to rehabilitate persons after liver transplantation.

Activities of daily living, Fatigue, Liver transplantation, Quality of life, Rehabilitation
dx.doi.org/10.1080/16501970500338771, hdl.handle.net/1765/62885
Scandinavian Journal of Rehabilitation Medicine
Department of Rehabilitation Medicine

van den Berg-Emons, H.J.G, Kazemier, G, van Ginneken, B.T.J, Nieuwenhuijsen, C, Tilanus, H.W, & Stam, H.J. (2006). Fatigue, level of everyday physical activity and quality of life after liver transplantation. Scandinavian Journal of Rehabilitation Medicine, 38(2), 124–129. doi:10.1080/16501970500338771