A systematic approach for uptake of evidence on sex-specific issues in guidelines - A pilot study
Journal of Evaluation in Clinical Practice (Print) , Volume 18 - Issue 2 p. 369- 377
Rationale, aims and objectives Increasing evidence indicates that sex-specific issues may have impact on prevention, diagnosis, or treatment. These issues are not systematically considered during the development of Dutch clinical practice guidelines. The aim of this study is to identify how members of guideline development groups discuss sex-specific evidence, and whether and how the outcomes of these discussions are reflected in the guideline. Methods Six guideline development committees (GDCs) were studied. Each committee was supported by a staff member from the guideline organization who was trained and received feedback to facilitate uptake of evidence on sex differences in the process of guideline development. Non-participant observation and transcription of audio recordings from 22 GDC meetings were performed. Content analysis of meeting transcripts and guidelines were studied to analyse characteristics of discussion episodes on sex-specific research data-based issues (subject matter, initiator and group approach towards the topic and themes) and whether or not conclusions on evidence were reflected in the final guideline text. Results Of the 87 identified discussion episodes, 68 dealt with sex-specific research evidence potentially relevant to guidelines. Respectively 51%, 28% and 21% of the latter episodes were initiated by committee members, staff members and chairpersons. Group approaches towards the subject matter were generally positive. Data from 60% of those episodes were reflected in the final guideline text. Sex-specific data on reproductive issues were more often discussed and reflected in guideline texts than data on other health issues. Discussion episodes on sex-specific evidence initiated by chairpersons were most often reflected in the guidelines. Conclusions This pilot study indicates that GDCs regularly focused on sex-specific issues. The participation of a trained staff member contributed to this.
|guideline development, guidelines, sex differences|
|Journal of Evaluation in Clinical Practice (Print)|
|Organisation||Department of Psychiatry|
Keuken, D.G, Bindels, P.J.E, Klazinga, N.S, & Haafkens, J.A. (2012). A systematic approach for uptake of evidence on sex-specific issues in guidelines - A pilot study. Journal of Evaluation in Clinical Practice (Print), 18(2), 369–377. doi:10.1111/j.1365-2753.2010.01591.x