The occurrence of severe fatigue after Guillain-Barré syndrome (GBS), and its relation with disease course, clinical characteristics, and antecedent infections was studied in 100 GBS patients. Severe fatigue, expressed as a mean Fatigue Severity Scale (FSS) score of 5.0 or more, was present in 60% of all patients. It was more frequently present in females and in patients over 50 years (p<0.01). There was no significant relationship between fatigue severity and the level of functional disability at nadir, antecedent events or infections, clinical variables, and time to follow-up after GBS.

Antecedent events, Disease severity, Fatigue, Guillain-Barré syndrome
dx.doi.org/10.1007/s00415-006-0163-6, hdl.handle.net/1765/62920
Journal of Neurology: official journal of the European Neurological Society
Department of Neurology

Garssen, M.P.J, van Koningsveld, R, & van Doorn, P.A. (2006). Residual fatigue is independent of antecedent events and disease severity in Guillain-Barré syndrome. Journal of Neurology: official journal of the European Neurological Society, 253(9), 1143–1146. doi:10.1007/s00415-006-0163-6